NOEL performs custom synthesis of polymer nanoparticles
We process your polymers into nanoparticles using our innovative particle synthesis technology “Two-Step Nano Splitting Method.” We specialize in the processing of nanoparticles smaller than 100 nm. We are particularly strong in our ability to fabricate ultra-small nanoparticles of 50 nm or less, which has been difficult to achieve with conventional technologies.
Two-Step Nano Splitting Method
Two-Step Nano Splitting Method is a unique nanoparticle synthesis technology based on a novel physical phenomenon “Spontaneous Droplet Nano Splitting.” An O/W (Oil in Water) emulsion is prepared from a polymer solution and pure water under soap free condition. Alcohol is then mixed in to adjust the surface tension of the solution droplets to zero. Due to the abrupt disappearance of surface tension, the solution droplets become unstable and spontaneously split into small pieces to form nanoparticles. The same procedure can be used to form uniform nano-emulsions.
NOEL’s Polymer Nanoparticles
３Three Key Features
01 Ultra-Small Size
The ability to synthesize nanoparticles of ultra-small size is the greatest feature of the two-step nano splitting method. It is possible to precisely control the size of nanoparticles to 50 nm or smaller, which has been difficult with conventional method.
- Size: 50 nm to smaller than 10 nm
- Precise control in 10 nm increment
- Monodisperse
02 Soap Free
Nanoparticles are synthesized without the use of any surfactants or other additives. Owing to a special treatment, the nanoparticles shows long term stability, despite being soap free.
- Additive Free
- Synthesized with pure water and alcohol
- Long-term stability (~several months)
03 High Versatility
The two-step nano splitting method uses solvent-solvent interactions to synthesize particles. It can be applied to any polymers as long as the solvent compatibility is appropriate, and the particle size is independent of the polymer.
- Particle synthesis based on Solvent-Solvent interaction
- Applicable to a wide range of polymers
- Particle size is independent of polymers
参考文献
- Two-step reprecipitation method with size and zeta potential controllability for synthesizing semiconducting polymer nanoparticles. Masaru Nagai,* Jun Huang, Dong Cui, Tiandong Zhou, Wei Huang. Colloid Polym. Sci.295, 1153–1164 (2017).
- Ultra-small polymer nanoparticles formed by instantaneous nano-splitting of surfactant-free mulsion. Jie Liu, Aoning Wang, Xiang Liu,* Wei Huang, Masaru Nagai* Langmuir 36, 7933-7942 (2020)
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